Abstract: Objective To investigate the safety and effectiveness of absorbable line in repair of gastroduodenal ulcer perforation. Methods Eighty patients undergoing acute perforation of gastroduodenal ulcer from February 2014 to February 2017 were divided into two groups，including 40 cases in control group and 40 cases in observation group. The control group repaired the ulcer perforation with silk sutures， and the observation group repaired the ulcer perforation with absorbable line. There were no statistically significant difference between the two groups in terms of preoperative general data，time of perforations， site of perforations，operation time and hospitalization time（P>0.05）. The ulcer healing was observed and analyzed in the two groups after 1 month，3 months and 12 months. Results In the observation group，the healing of ulcer was significantly different from that in the control group under gastroscope（P<0.05）. Conclusion It is safe and feasible to perform repair of gastroduodenal ulcer perforation by using absorbable line，which could promote ulcer healing.

Key words: gastroduodenal ulcer perforation, repair, absorbable line

摘要： 目的 探讨可吸收线在胃十二指肠溃疡穿孔修补术中应用的安全性及有效性。方法将2014 年2 月~2017 年2 月收治的80 例急性胃十二指肠溃疡穿孔患者作为研究对象进行前瞻性研究。分为对照组和观察组，每组 40 人。对照组用丝线修补溃疡穿孔，观察组用可吸收线修补溃疡穿孔。两组患者性别、年龄、穿孔时间、穿孔部位、手术时间、住院时间等方面无明显差异（P>0.05）。对比分析两组术后 1 个月、3 个月、12 个月溃疡愈合情况。结果 观察组胃镜下溃疡愈合情况与对照组差异显著，有统计学意义（P<0.05）。结论 可吸收线用于胃十二指肠溃疡穿孔修补安全、有效，可促进溃疡愈合。

关键词: 可吸收线, 修补, 胃十二指肠溃疡穿孔