Abstract: ［Abstract］ Objective To compare the efficacy of 1% Mepivacaine with 0.5% ropivacaine on brachial plexus nerve block in clavicle fracture surgery. Methods Thirty adult patients（ASAI~II）undergoing clavicle fracture surgery were randomly divided into two groups（n=15），1% mepivacaine group（group M）and 0.5% ropivacaine group（group R）. Patients in two groups both acceptted brachial plexus nerve block guided by nerve stimulator，and patients in group M and group R were injected 1% mepivacaine or 0.5% ropivacaine 25 ml separately. The hemodynamic，sensory and motor block onset and recovery time， postoperative VAS score，adverse reactions and anesthesia satisfaction were observed in the two groups. Results Compared with group R，the onset time of sensory and motor block was shortened in group M， the time of block recovery was shortened（P<0.05），and the scores of 6 h and 12 h were increased（P< 0.05）after operation（VAS < 0）. Conclusion Brachial plexus nerve block with 1% mepivacaine and 0.5% ropivacaine both can satisfy clavicle fracture surgery. The use of 1% mepivacaine was faster than the 0.5% ropivacaine，and the sensory and motor recovery was earlier in group M，which was beneficial to the early stage of operation，but the analgesic effect was less than 0.5% ropivacaine.

Key words: brachial plexus nerve block, clavicle fracture, ropivacaine, mepivacaine

摘要： ［摘要］ 目的 观察1%甲哌卡因与0.5%罗哌卡因用于肌间沟臂丛神经阻滞锁骨骨折术中麻醉效果的比较。方法 择期行肌间沟臂丛神经阻滞锁骨骨折成年患者30 例，ASAI~II 级，随机分为组（n=15）；1%甲哌卡因组（M 组）和 0.5%罗哌卡因组（R 组）。两组均在神经刺激仪引导下，以肌间沟入路行臂丛神经阻滞，M 组和R 组分别注入 1%甲哌卡因 25 mL 和 0.5%罗哌卡因 25 mL。观察两组血流动力学，感觉、运动阻滞起效及恢复时间，术后 VAS 评分，不良反应及麻醉满意度。结果 与R 组比较，M 组感觉、运动阻滞起效时间缩短，阻滞恢复时间缩短（P<0.05），术后6 h、 12 h 的 VAS 评分增加（P<0.05）。结论 1%甲哌卡因与 0.5%罗哌卡因行肌间沟臂丛神经阻滞， 均能满足锁骨骨折手术。采用 1%甲哌卡因较 0.5%罗哌卡因起效更快，且感觉、运动恢复更早， 利于早期活动，但术后镇痛效果不如0.5%罗哌卡因。

关键词: 肌间沟臂丛神经阻滞, 甲哌卡因, 罗哌卡因, 锁骨骨折