Abstract: Objective To summarize the clinical characteristics and therapeutic Methods ofinsulinomain our Department in order that we couldoptimize its treatmentincorporate with the advancement in associated medical areas. Methods Five cases of insulinomain our Department during the past 10 years were followed-up and analyzed retrospectively. Results The incidence rate of insulinoma was very low，misdiagnosis may found in out-patient clinic without the laboratory and imaging examination. Radical resection under the guide of ultrasound provided a better prognosis and treatment with insulinomapatients. Conclusion Insulinoma is worth of consideration of clinicians though its incidence rate is low. The individualizedsurgical treatment is the first choice forinsulinoma.

Key words: insulinoma, diagnosis

摘要： 目的 总结我科近10年收治的5例胰岛素瘤（insulinoma）的治疗经过，结合本领域的诊治技术进步而进一步总结其特点。方法 回顾性分析我科近10年收治的5例胰岛素瘤患者的临床资料包括症状，诊治经过及随访情况。结果 胰岛素瘤人群总体发病率低，虽常有门诊误诊但通过实验室和影像学检查均能确诊。结合术中超声定位行外科根治切除为最佳治疗手段，病人预后较好。结论 胰岛素瘤发病率低但值得临床医生重视。虽外科切除是首选治疗方案，仍需根据具体肿瘤特点而采取个体化治疗方案。

关键词: 诊治, 胰岛素瘤