Abstract: 【Abstract】〓Objective〓To investigate the effect of lauromacrogol for oral and maxillofacial hemangioma. Methods〓Ninety patients with oral and maxillofacial hemangioma were assigned to four groups including sodium morrhuate,bleomycin,lauromacrogol group. The clinical effects and adverse reactions were observed in three groups. Results〓In sodium morrhuate group, 10 cases were cured, 15 cases were markedly effective, 3 case effective, 2 cases lost. In bleomycin group, 11 cases were cured, 10 cases were markedly effective, 6 cases effective, 3 cases lost. In lauromacrogol group 18 cases were cured, 7 cases were markedly effective, 3 cases effective, 2 cases lost. There were statistical differences between effective treatment and adverse reactions such as abdominal discomfort and low fever. Conclusion〓In the treatment of oral and maxillofacial hemangioma, lauromacrogol is characterized by explicit therapeutic effects, few side effects and less adverse reactions, so it deserves to be popularized and applied in clinical practice.

Key words: Lauromacrogol, Infant, Oral and maxillofacial hemangioma

摘要： 【摘要】 目的 探讨血管畸形局部注射聚桂醇的治疗效果。方法 所有病例均来源于经我院治疗的婴幼儿颌面部血管畸形,病历及随访资料完整,选择的90例血管畸形患儿分组,鱼肝油酸钠治疗组(30例),博莱霉素治疗组(30例),聚桂醇治疗组(30例)。观察各组治疗情况及不良反应。随访观察,并评价其疗效。结果〓随访时间4~13个月,鱼肝油酸钠患儿中治愈10例、显效15例、有效3例,2例未能坚持治疗。博莱霉素治愈11例、显效10例、有效6例,3例未能坚持治疗。聚桂醇组治愈18例、显效7例、有效3例,2例未能坚持治疗。聚桂醇组疗效与前两组相比无明显差异,聚桂醇组副作用小,差异具有统计学意义。结论〓以聚桂醇为主的硬化剂局部注射治疗血管畸形疗效较好,副作用少。

关键词: 颌面部血管畸形, 婴幼儿, 聚桂醇