Abstract: 【Abstract】〓Objective〓To study using nano-carbon in near-total or total thyroidectomy to protect the parathyroid glands..Methods〓Eighty patients of large goiter,.multinodular goiter and thyroid cancer were performed near-total or total thyroidectomy using nano-carbon to identify parathyroid glands..Results〓Parathyroid gland was not found in 78 species pathologically..Two cases were confirmed malignant tumor because of tumor invasion..All patients were examied and showed normal parathyroid hormone level in half an hour, 6 hours and 24 hours after surgery. Conclusion〓The use of nano-carbon in near-total or total thyroidectomy can avoid or reduce the injury of parathyroid glands.

Key words: Nano-carbon, Parathyroid gland, Near-total or total thyroidectomy

摘要： 【摘要】 目的 探讨应用纳米碳混悬液(简称纳米碳)对提高甲状腺近全/全切除手术的精准性、降低术中损伤甲状旁腺的价值。方法〓选取巨大结节性甲状腺肿、满布结节的结节性甲状腺肿以及甲状腺癌患者共80例行甲状腺近全/全切除术,术中游离部分带状肌显露甲状腺上下极内侧部分后,于甲状腺上下极注射纳米碳混悬液各0.1 mL,待甲状腺和周围淋巴组织染色后常规行甲状腺手术,术中识别未被染色的甲状旁腺并予以保护。结果〓80例中78例病理标本中无甲状旁腺组织,2例甲状腺癌(术中证实下旁腺被肿瘤浸蚀)见旁腺组织。所有患者术后半小时、6小时、24小时复查甲状旁腺素均位于正常值范围。结论〓甲状腺(近)全切除手术中使用纳米碳可有效的将甲状腺组织与甲状旁腺区分,避免或减少甲状旁腺损伤。

关键词: 纳米碳, 甲状旁腺, 甲状腺全切除, 甲状腺近全切除