Abstract: 【Abstract】〓Objective〓To analyze postoperative complications of pancretoduod-enectomy (PD). Methods〓A retrospective review of 154 consecutive patients who underwent PD with pancreaticojejuno-stomy in recent 10 years was divided into the recent group of 105 cases and the long term group of 49 cases. Results〓The surgery-related complications was 18.1% in the recent group while was 32.7% in the long term group. The leak rate in the recent group was 4.8% and in the long term group 16.3%. The mean operation time in the recent group was 213.34±66.98 min and in the long term group 250.34±67.26 min. The mean hospital length of stay after PD was longer in the long term group (22.76±9.73)d as compared to the recent group.(18.45±7.11 d, P<0.05)..However there were no significant differences in bile fistula occurrence,.gastrointestinal and intraa-bdominal hemorrhage,gastroparalysis and infection, mortality and reoperation rate, operation time and intaoperative blood loss between the two groups..Conclusion〓Leakage of pancreatic is the key factor for the postoperative complications of PD, standard treatment, professional operation can effectively reduce the postoperative complications of PD.

Key words: Pancreatoduodenectomy, Pancreaticojejunostomy, Pancreatic fistula

摘要： 【摘要】 目的 探讨如何降低胰十二指肠切除术(PD)术后并发症。方法〓回顾性分析近10年来本科154例行PD病例的临床资料,分为近期组105例,远期组49例。结果〓术后主要并发症(近期组,18.1%,远期组,32.7%)、胰漏(近期组,4.8%,远期组,16.3%)、手术时间(近期组,213.34±66.98 min,远期组,250.34±67.26 min)、术后平均住院时间(近期组:18.45±7.11 d,远期组:22.76±9.73)d)均有统计学差异(P<0.05),而胆漏、出血、腹腔感染、胃排空延迟、死亡率、再手术率、手术时间、术中失血尽管有差异但无统计学意义。结论〓胰漏是PD术后并发症关键因素,规范化、专业化手术治疗可有效减少PD术后并发症。

关键词: 胰十二指肠切除术, 胰肠吻合术, 胰漏