Abstract: 【Abstract】〓Objective〓To explore the treatment effect and complication therapy of laparoscopic splenectomy and esophagogastric devascularization for portal hypertension. Methods〓The clinical data of 38 cases from January 2010 to March 2014 who underwent laparoscopic splenectomy and esophagogastric devascularization for liver cirrhosis and portal hypertension were analyzed. Results〓All operations in this study were performed successfully. The operation time was 238.42±75.25 min,.the blood loss during operation was 200.53±90.81 ml,.the total hospital stay was 22.71±7.19 d,.the postoperative hospital stay was 12.18±4.49 d,.and the recovery time of gastrointestinal function was 3.45±0.89 d. There were no significant differences in liver function between the preoperative and postoperative data. While the postoperative levels of PLT were significantly higher (48.2±19.7 vs. 227.5±80.5,P<0.001). During the follow-up, rebleeding occurred in 6 cases, hepatic encephalopathy occurred in 3 cases,.portal vein thrombosis occurred in 12 cases,.pancreas abscess occurred in 1 case..All complications were treated in conservative way and the patients got recovery. Conclusion〓Laparoscopic splenectomy and esophagogastric devascularization is a safe,.effective,.minimally invasive procedure for the management of portal hypertension.

Key words: Liver cirrhosis, Portal hypertension, Laparoscopic splenectomy and esophagogastric devascularization

摘要： 【摘要】〓目的〓探讨腹腔镜脾切除加贲门食管周围血管离断术的疗效以及术后并发症的预防与处理。方法〓回顾性分析2010年1月~2014年3月应用腹腔镜脾切除加贲门食管周围血管离断术治疗的38例肝炎后肝硬化伴门静脉高压症病例的临床资料。结果〓所有病例均成功完成手术。手术时间238.42±75.25 min,术中出血量200.53±90.81 mL,总住院时间22.71±7.19 d,术后住院时间12.18±4.49 d,术后胃肠动力恢复时间3.45±0.89 d。手术前后肝功能结果无明显差异,而PLT术后明显升高(48.2±19.7 vs. 术前227.5±80.5,P<0.001)。随访过程中有6例发生再出血,3例发生肝性脑病,12例发生门静脉血栓,1例胰尾脓肿均经保守治疗后好转。结论〓腹腔镜脾切除加贲门食管周围血管离断术是一种安全,有效,且创伤小的门静脉高压症治疗手段。

关键词: 肝硬化, 门静脉高压症, 腹腔镜脾切除加贲门食管周围血管离断术