Abstract: 【Abstract】〓Objective〓To investigate the clinical efficacy and safety profiles of compound lidocaine for surgical incision analgesia. Methods〓200 cases underwent operation in surgical ward of our hospital from June 2012 to June 2014 were divided into observation group(100 cases) and control group(100 cases), and the observation group was given compound lidocaine for incision analgesia, the control group was given conventional suture. VAS score,wound healing situation and relative complications were compared between two groups. Results〓VAS score of observation group at 6 h,12 h,24 h,48 h were significant lower than control group(P<0.05), but there were no significant differences between two groups in incision exudation, incision infection, remove time of stitches and incision healing situation (P>0.05),..and the total patients of supplementation of analgesic drugs of observation group were significant lower than control group (P<0.05). Conclusion〓Compound lidocaine for surgical incision analgesia has good and lasting analgesia effect, low medical cost and easy operability.

Key words: Lidocaine, Compound, Incision, Analgesia, Safety

摘要： 【摘要】〓目的〓探讨复方利多卡因在术后切口镇痛中的应用疗效、可行性及安全性。方法〓收集我院外科系统2012年6月~2014年6月的200例手术患者为研究对象,按照随机化原则分为观察组和对照组,观察组的100例采用复方利多卡因切口皮下浸润注射,对照组的100例行常规缝合,观察并比较两组VAS评分、伤口愈合情况及相关并发症差异。结果〓两组VAS评分比较发现:观察组术后6 h、12 h、24 h、48 h各时间点的VAS评分均明显低于对照组,差异有统计学意义(P<0.05)。两组切口渗出、切口感染、拆线时间和切口愈合等级情况比较差异无统计学意义(P>0.05),追加镇痛例数观察组明显低于对照组,两组比较差异有统计学意义(P<0.05)。结论〓采用复方利多卡因术后切口周围皮下浸润注射可达到良好而持久镇痛效果,具有较好临床疗效及安全性,且医疗成本低廉、临床易于操作,值得临床推广应用。

关键词: 利多卡因, 复方, 切口, 镇痛, 安全性