Abstract: The gallbladder is extremely rare involved by metastatic carcinoma from other organs. To our knowledge, there is no case of matastasis to gallbladder from cervical carcinoma being reported and no systemic diagnosis and treatment standards. A 49-year-old woman presented pain in her upper abdomen for more than 20 days with a previous history of radical hysterectomy. A computed tomography（CT） scan of upper abdomen revealed an acute cholecystitis. Laparoscopic exploration was performed,swollen lymph nodes in portal area were seen during the operation. A lymph node metastasis was suggested by rapid frozen section examination. Radical resection of gallbladder caner was performed and the final pathological examination showed the metastatic cervical squamous carcinoma to the gallbladder. The patient was treated with hyperthermic intraperitoneal chemotherapy（HIPEC）effectively. In conlusion, the diagnosis of metastatic gallbladder malignant tumor is difficult without systematic diagnosis and treatment standards. For patients with cholecystitis with a history of previous malignant tumors and poor response to long-term conservative treatment, clinicians need to pay more attention to avoid missed diagnosis and misdiagnosis.

Key words: gallbladder, metastatic carcinoma, cervical carcinoma, diagnosis, treatment

摘要： 转移性胆囊恶性肿瘤是一种罕见疾病,宫颈癌转移至胆囊目前尚未见病例报道。本文报告一例。49岁女性患者,因上腹部疼痛20余天来诊,既往子宫颈癌手术病史。术前腹部CT诊断为慢性胆囊炎急性发作,予行腹腔镜探查术,术中见肝门区肿大淋巴结,快速冰冻病理提示淋巴结转移癌,术中诊断胆囊癌,予行胆囊癌根治术并留置腹腔热灌注管,术后病理提示为宫颈癌胆囊转移,术后行腹腔热灌注化疗治疗,效果良好。总结经验,转移性胆囊恶性肿瘤诊断困难,缺乏系统性的诊治规范,对于既往合并恶性肿瘤病史、长期保守治疗效果欠佳的胆囊炎患者,需要临床医生多加鉴别,避免漏诊、误诊。

关键词: 胆囊, 转移性肿瘤, 宫颈癌, 诊断, 治疗