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Lingnan Modern Clinics In Surgery ›› 2021, Vol. 21 ›› Issue (05): 571-573.DOI: 10.3969/j.issn.1009-976X.2021.05.016

• Original Articles and Clinical Research • Previous Articles     Next Articles

The diagnostic ability of the mean CT value for pulmonary ground glass nodules which less than 1 cm

CHEN Shuai, ZHANG Wei, YIN Lei, YU Qing-hua, MA Ming-ping   

  1. Department of Radiology, Fujian Provincial Hospital, Fujian Fuzhou 350001, China
  • Contact: YU Qing-hua,15859043670@163.com; MA Ming-ping, 448126163@qq.com

平均CT值测量对小于1 cm肺磨玻璃结节的诊断价值

陈帅, 张玮, 殷磊, 余庆华*, 马明平*   

  1. 福建省立医院放射科,福州 350001
  • 通讯作者: *马明平,Email:15859043670@163.com;余庆华,Email:448126163@qq.com
  • 基金资助:
    福建省自然科学基金(2018J01243)

Abstract: Objective To evaluate the diagnostic ability of the mean CT value for pulmonary ground glass nodules which were less than 1 cm. Methods We retrospectively evaluated 216 patients with ground glass nodules less than 1 cm between 2016 and 2020. All these ground glass nodules were resected and pathologically diagnosed. The mean CT value were measured in picture archiving and communication system(PACS) and its optimal cut-off point for the mean CT value was analyzed with receive operating characteristic(ROC) curve. Results The mean CT value of inflammatory lesion group was -782 ~ -377(-595.9±122.3) Hounsfield units(HU), which was lower than lung adenocarcinoma group which the mean CT value was -807 ~ -57(-494.3±157.4)HU(t=-2.190,P<0.05). The cut-off point was -604 HU, the sensitivity was 73.5% and the specificity was 67.3%, the area under curve(AUC) was 0.69. The mean CT value of the preinvasive group was -807 ~ -111(-540.1±131.1)HU, and The mean CT value of the invasive group was -807 ~ -57(-464.8±166.2)HU. The difference between the two group statistically significant (t=-2.66,P<0.05). The cut-off point was -473 HU, the sensitivity was 50.8% and the specificity was 75%, the AUC was 0.64. Conclusion Themean CT value is valuable in the differential diagnosis of benign and malignant lesion in the ground glass nodules which was less than 1 cm, and it is helpful to judge the invasiveness of the lung adenocarcinoma.

Key words: lung ground glass nodules, tography, X-ray computer

摘要: 目的 探讨平均CT值测量对小于1 cm磨玻璃结节的诊断价值。方法 回顾性分析我院2016年1月至2020年1月经CT检查和手术切除的小于1cm的磨玻璃结节216例,利用医学影像存储和传输系统工作站,在薄层扫描肺窗图像上测量磨玻璃结节平均CT值,并通过ROC曲线确定最佳临界CT值。结果 炎性病变组平均CT值-782~-377(-595.9±122.3)HU低于肺腺癌组-807~-57(-494.3±157.4)HU(t=-2.190,P<0.05),最佳临界值为-604 HU,敏感度、特意度分别为73.5%、67.3%,AUC值为0.69。浸润前病变组CT值-807~-111(-540.1±131.1)HU与浸润性病变组CT值-807~-57(-464.8±166.2)HU有统计学差异(t=-2.66,P<0.05),最佳临界值-473 HU,敏感度、特意度分别为50.8%、75%,AUC值为0.64。结论 平均CT值测量在小于1 cm磨玻璃结节良恶性诊断中有一定的应用价值,并对判断肺腺癌是否浸润性具有一定的应用价值,为临床诊疗提供重要参考依据。

关键词: 肺磨玻璃结节, 体层摄影技术, X线计算机

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