Photodynamic therapy of cholangiocarcinoma

doi:10.3969/j.issn.1009-976X.2021.05.001

Abstract

摘要： 胆管癌是种恶性程度很高的消化道肿瘤,且超过一半的患者在诊断时已是疾病晚期,错失了手术的机会。光动力疗法（PDT）是一种局部消融方法,它使用系统性光敏剂,优先聚集在恶性细胞中,并被非热光激活,通过氧自由基介导的过程导致恶性细胞的破坏。胆管癌的PDT潜在治疗方案包括联合化疗、联合支架植入、复发肿瘤的术后治疗,或对患者进行治疗使肿瘤降期后行根治性手术。在治疗胆汁淤积的同时,PDT疗法可提高生存率和生活质量,并减少肿瘤生长。

关键词: 胆管癌, 光动力疗法, 肝切除, 支架, 化疗, 肝移植

CLC Number:

R735.8

LIU Zhao⁃yuan, JIANG Xiao⁃feng, XUE Ping. Photodynamic therapy of cholangiocarcinoma[J]. Lingnan Modern Clinics In Surgery, 2021, 21(05): 495-499.

刘钊远, 蒋小峰, 薛平. 胆管癌的光动力治疗[J]. 岭南现代临床外科, 2021, 21(05): 495-499.

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