Diagnosis and treatment of undifferentiated sarcoma of the liver in adults： a case report and the literature review

doi:10.3969/j.issn.1009-976X.2021.03.021

Abstract

Abstract: Undifferentiated sarcomas of the liver in adults USL is very rare. Its pathogenesis is not clear and its clinical features are not typical, mainly with abdominal mass and pain as the common symptoms. The result of CT and MRI are characterized by multiple small cystic solid masses. In this paper, the diagnosis and treatment process of a 55-year-old man with primary undifferentiated sarcoma of the liver, and the clinical and pathological characteristics of USL and comprehensive treatment methods such as ablation and hepatectomy were reviewed。

Key words: liver, undifferentiated sarcoma, ablation, hepatectomy, comprehensive treatment

摘要： 成人肝脏未分化肉瘤（USL）非常罕见,其发病机制尚未明确,临床特征不典型,主要以腹部肿块和疼痛为常见症状,CT及MRI以多发性小囊实性肿块为特征,本文以1例55岁中年男性原发性肝脏未分化肉瘤的诊疗过程,并通过文献复习USL的临床、病理等特征及以消融、肝切除等综合治疗方法。

关键词: 肝脏, 未分化肉瘤, 消融, 肝切除, 综合治疗

CLC Number:

R735.7

LI Hao-quan, YE Zhen-wei, CHEN Shi-xing, JIANG Jing-zhu, WANG Zai-guo. Diagnosis and treatment of undifferentiated sarcoma of the liver in adults： a case report and the literature review[J]. Lingnan Modern Clinics In Surgery, 2021, 21(03): 349-351.

李浩权, 叶振伟, 陈施性, 蒋金柱, 王在国. 成人肝脏未分化肉瘤的诊治——1例报告并文献复习[J]. 岭南现代临床外科, 2021, 21(03): 349-351.

References

[1] Wu Z, Wei Y, Cai Z, et al.Long-term survival outcomes of undifferentiated embryonal sarcoma of the liver: a pooled analysis of 308 patients[J]. ANZ J Surg, 2020, 90(9):1615-1620.
[2] Wu Z, Wei Y, Cai Z, et al.Long-term survival outcomes of undifferentiated embryonal sarcoma of the liver: a pooled analysis of 308 patients[J]. ANZ J Surg, 2020, 90(9):1615-1620.
[3] Zhang C, Jia CJ, Xu C, et al.Undifferentiated embryonal sarcoma of the liver: Clinical characteristics and outcomes[J]. World J Clin Cases, 2020, 8(20):4763-4772.
[4] Martins-Filho SN, Putra J. Hepatic mesenchymal hamartoma and undifferentiated embryonal sarcoma of the liver: a pathologic review [J]. Hepat Oncol, 2020, 7(2):HEP19.
[5] Shu B, Gong L, Huang X.Undifferentiated embryonal sarcoma of the liver in adults: Retrospective analysis of a case series and systematic review[J]. Oncol Lett, 2020, 20(4):102.
[6] Minami K, Sakoda M, Iino S, et al.A Case of Adult Undifferentiated Sarcoma of the Liver with Intraatrial Metastasis[J]. Gan To Kagaku Ryoho, 2018, 45(4):721-724.
[7] Gerson G, Valença JT, Cavalcante JM, Coêlho RAB.Undifferentiated embryonal sarcoma of the liver in elderly: Case report and review of the literature[J]. Indian J Pathol Microbiol, 2019, 62(1):129-131.
[8] 应小平,王敏,张晓丽,等. 肝未分化肉瘤--附1例报道报告并文献复习[J]. 陕西肿瘤医学,2001,9(2):129,143.
[9] 张向华,晏建军,周飞国,等. 肝未分化肉瘤的诊断与治疗(附7例报告)[J]. 肝胆外科杂志,2006,12(2):105-107.
[10] Mori A, Fukase K, Masuda K, et al.A case of adult undifferentiated embryonal sarcoma of the liver successfully treated with right trisectionectomy: a case report[J]. Surg Case Rep, 2017, 3(1):19.
[11] Schepelew D, Reese T, Horling K, et al.Undifferentiated embryonal sarcoma of the liver treated with associating liver partition and portal vein ligation for staged hepatectomy in a young adult: A case report[J]. Int J Surg Case Rep, 2020, 66:221-227.
[12] Esteban SG, Emilio CU, Emmanuel AF, et al.Undifferentiated embryonal sarcoma of the liver in adult patient: A report of two cases[J]. Ann Hepatobiliary Pancreat Surg, 2018, 22(3):269-273.
[13] Shi M, Xu H, Sangster GP, et al.Pulmonary Metastases from an Undifferentiated Embryonal Sarcoma of the Liver: A Case Report and Review[J]. Case Reports Case Rep Oncol Med, 2018, 2018:7840865.
[14] Dueñas D, Huanca L, Cordero M, et al.Undifferentiated (embryonal) liver sarcoma: reviaew of 6 cases in National Cancer Institute, Lima, Peru. Review of the literature[J]. Rev Gastroenterol Peru, 2016, 36(1):71-76.
[15] Ahmed M, Solbiati L, Brace CL, et al.Image-guided tumor ablation: standardization of terminology and reporting critertia-a 10-year update[J]. Radiology, 2014, 273(1): 241-260.
[16] Hu HM, Zhang WL, Li J, et al.Report of seven children with undifferentiated embryonal sarcoma of the liver[J]. Chin Med J (Engl), 2019, 132(18):2244-2245.
[17] Ma L, Liu YP, Geng CZ, et al.Undifferentiated embryonal sarcoma of liver in an old female: case report and review of the literature[J]. World J Gastroenterol, 2008, 14(47):7267-7270.
[18] Gao J, Fei L, Li S, et al.Undifferentiated embryonal sarcoma of the liver in a child: A case report and review of the literature[J]. Oncol Lett, 2013, 5(3):739-742.
[19] Perl RM, Häring A, Horger MS, et al.Paraneoplastic syndrome in undifferentiated embryonic sarcoma of the liver[J]. EJNMMI Res, 2020, 10(1):11.
[20] 胡丙洋,张雯雯,周黔川,等. 巴塞罗那C期肝癌靶向联合免疫降期转化后实施左半肝切除1例[J]. 中华肝胆外科杂志, 2020, 26(1): 65-67.
[21] 徐勋华,王夏武,周义成. 成人肝未分化肉瘤的CT诊断(附3例报告及文献复习)[J]. 临床放射学杂志, 2012, 31(11): 1675-1677.