Abstract: Objective Transumbilical single-incision laparoscopic-assisted appendectomy （TSLAA） was a surgical technique that used a combined intra- and extracorporeal method for acute appendicitis. The aim of this study was to compare the clinical outcome and safety between TSLAA and traditional laparoscopic appendectomy （LA）. Methods Patients with acute appendicitis between January 2017 and October 2019 who underwent laparoscopic appendectomy and received perioperative enhanced recovery after surgery （ERAS） protocal were analyzed retrospectively. All the enrolled patients were divided into two groups according to different surgical methods： TSLAA （47 cases） and LA （92 cases）. The perioperative parameters were compared between two groups. Results TSLAA group and LA group was comparable in terms of preoperative general information and cases in TSLAA group had lower BMI and shorter duration of abdominal pain. No differences were found in operation time and intraoperative blood loss between two goups. Only one case in TSLAA group was converse to LA. A better pain control and satisfaction score during hospitalization were noticed in TSLAA group. Postoperative recovery of gastrointestinal functions were similar between two groups. The incidences of overall complication tended to be lower in TSLAA group, however no statistical differences were found between two groups. Moreover, patients in the TSLAA group had intraoperative cost （5863.4 yuan） and perioperative expenses （6354.3 yuan）. Conclusion TSLAA was a safe and feasible technique and it may be a useful more minimally invasive alternative to acute appendicitis

Key words: laparoscopic appendectomy, acute appendicitis, transumbilical single-incision laparoscopic-assisted appendectomy

摘要： 目的 比较腹腔镜辅助阑尾切除术（TSLAA）与传统腹腔镜阑尾切除术（LA）的临床疗效和安全性。方法 回顾性分析2017年1月至2019年10月行腹腔镜阑尾切除术且围手术接受加速康复外科（ERAS）方案的急性阑尾炎患者,并根据手术方式分为两组：TSLAA组（47例）和TLA组（92例）。分析比较两组围手术期资料的异同。结果 TSLAA组与LA组在术前一般资料方面具有可比性;TSLAA组的病人术前BMI较低,腹痛持续时间较短。两组患者手术时间及术中出血量无差异。TSLAA组患者在住院期间疼痛控制及满意度评分均优于LA组。但两组术后胃肠功能恢复情况相似。TSLAA组总并发症、感染性并发症、非感染性并发症发生率低于LA组,但并无统计学差异。TSLAA组术中、围手术期费用均明显低于LA组（P<0.05）。结论 TSLAA是一种安全可行的技术,是急性阑尾炎的另一种有效且微创的选择。

关键词: 急性阑尾炎, 经脐单切口腹腔镜辅助阑尾切除术, 腹腔镜阑尾切除术