Abstract: Objective To investigate the risk factors for the risk of thyroid nodules. Methods A total of 240 patients in the health examination department of our hospital were surveyed. The questionnaires were used to analyze the age， sex， family style and living habits of the patients. The age， sex， family history and habits of patients with thyroid nodules and no thyroid nodules were compared. Multivariate logistic regression analysis was used to analyze the risk factors of thyroid nodules. Results The three factors of gender， head and neck irradiation and psychology were related to the disease of thyroid nodules. The results of single factor analysis showed that people with head and neck irradiation history， female patients and personality depression were risk factors for thyroid disease. The final inclusion of the model is the high-risk factors for thyroid nodules， including gender， head and neck exposure and personality. Conclusion Gender， head and neck exposure history and personality may be risk factors for thyroid nodules.

Key words: questionnaires, thyroid nodules, high risk factors, multi-actor analysis

摘要： 目的 探讨甲状腺结节发病的高危风险因素。方法 调查240例在我院保健科体检的患者，问卷调查患者年龄、性别、家族史以及生活习惯等，对比研究有甲状腺结节和无甲状腺结节的患者的年龄、性别、家族史以及生活习惯等差别。采用多因素的二分类Logistic回归分析甲状腺结节发病原因的高危因素。结果 性别、头颈照射和性格等三个因素与甲状腺结节的患病有关，单因素分析结果显示，有头颈部照射史、女性患者和性格忧郁的人群是甲状腺发病的危险因素，多因素分析中最终纳入模型的是性别、头颈照射史和性格等三个因素为甲状腺结节发病的高危风险因素。结论 性别、头颈部照射史以及性格等可能是甲状腺结节发病的风险因素。

关键词: 甲状腺结节, 高危因素, 问卷调查, 多因素分析