Abstract: The mortality rate of subarachnoid hemorrhage （SAH） caused by aneurysm rupture can be as high as 32% to 67%, with approximately 30% of patients suffering from moderate to severe disability. With advancements in imaging diagnostic techniques, an increasing number of unruptured intracranial aneurysms （UIAs） are being detected, providing clinicians with more opportunities for preventive interventions before rupture. There are many risk factors for predicting UIA rupture, such as morphological factors like the location and size of the aneurysm, as well as hypertension, hyperlipidemia, and other factors. However, none of these can objectively evaluate the risk of rupture individually or provide more insights for treatment decision-making. Moreover, the relationships between various factors are intricate, making it very difficult to establish reliable and precise predictive models. This article provides a brief overview of the more common risk factors for UIA rupture.

Key words: unruptured intracranial aneurysm, rupture risk, risk factors, epidemiology

摘要： 动脉瘤破裂引起的蛛网膜下腔出血（SAH）病死率高达32%~67%,约有30%病人会遗留中、重度残疾。随着影像诊断技术的进步,越来越多的（UIA）被检出,给临床医师在其破裂之前进行预防干预提供了更多机会。预测UIA破裂的风险因素较多,如动脉瘤的位置、大小等形态学因素及高血压、高血脂等因素,但都无法单一对破裂风险进行客观评价并提供更多治疗决策方面的提示。况且各种因素之间关系错综复杂,建立可靠精确预测的标准预测模型十分困难,特对较常见的UIA破裂风险因素进行简述。

关键词: 未破裂颅内动脉瘤, 破裂风险, 风险因素, 流行病学