Abstract: Objective To compare the clinical effect between the minimally invasive resection and traditional open resection after steroid hormone therapy for granulomatous mastitis. Methods The record of 166 patients with granulomatous mastitis were collected from March 2016 to December 2019. Eighty-six patients in observation group were treated by ultrasonic-guided vacuum-assisted resectionand 80 patients in control group were treated by traditional open resection, and those with larger cavities underwent free flap plasty and indwelling drainage tube. The recurrence rate, appearance satisfaction, hospitalization time and treatment cost between two groups were recorded. Results The recurrence rate of observation group was 3.49% （3/86） and 3.75% （3/80） in control group. There was no significant difference between two groups （P=0.93）, and the observation group have advantage in appearance satisfaction, hospitalization time and treatment cost compare to the control group. Conclusion The ultrasonic-guided vacuum-assisted resection is as effective as traditional open resection with economic advantages, which worth clinical application and promotion.

Key words: granulomatous mastitis, vacuum assisted resection, ultrasonic guided

摘要： 目的 对照研究肉芽肿性乳腺炎激素治疗后行超声引导下真空辅助旋切微创手术与行开放手术治疗的临床效果。方法 选取2016年3月至2019年12月收治肿块型肉芽肿性乳腺炎患者166例,分为微创手术组（观察组）86例及开放手术组（对照组）80例。观察组应用乳腺真空辅助旋切系统在超声引导下切除病灶。对照组采用开放手术切除病灶,术腔较大者行任意皮瓣成形术并留置引流管。观察两组复发率、外观满意度、住院时长及治疗费用。结果 观察组复发率3.49%（3/86）,对照组复发率3.75%（3/80）,两组复发率相比较,无统计学差异（P=0.93）。外观满意度、住院时间及治疗费用则观察组优于对照组。结论 超声引导下真空辅助旋切微创手术治疗肉芽肿性乳腺炎临床效果不亚于开放手术,美容效果好、住院时间短且治疗费用低。

关键词: 肉芽肿性乳腺炎, 真空辅助旋切术, 超声引导