Abstract:

 Objective To investigate the effect and safety of preoperative percutaneous transhe-patic biliary drainage（PTBD）for the patients with hilar cholangiocarcinoma underwent operative treat-ment. Methods A total of 56 patients with hilar cholangiocarcinoma underwent operative treatment between January 2006 and December 2016, in whom 32 patients were subjected to PTBD before surgery （PTBD group）and 24 patients without PTBD were assigned to controls. The changes of the perioperative indicators were compared between two groups of patients. Results The total bilirubin of PTBD group was 286 ± 134 umol/L before PTBD treatment, which was significantly reduced to 153 ± 96 μmol/L after treatment （P<0.05）. Moreover there was no significant difference of the incidence with blood loss intraoperative, the bacteria infection of bile and postoperative complications between the two groups. Conclusion PTBD is a safe and effective method to alleviate jaundice for the patients with hilar cholan-giocarcinoma before operation, which can improve the patient’s liver function, systemic general situation and the tolerance of the surgery.

Key words: hilar cholangiocarcinoma, PTBD, operation, effect and safety

摘要：

 目的  探讨术前下经皮经肝胆管穿刺置管引流术（PTBD）对拟行手术治疗的肝门 部胆管癌患者的疗效及安全性。方法  选择 2006 年 1 月至 2016 年 12 月行手术治疗的肝门部胆管 癌患者 56 例，其中 PTBD 组 32 例，对照组为 24 例没有实施 PTBD 患者，比较两组患者围手术期有关 指标的变化情况。结果  PTBD 组引流前后总胆红素分别为 286±134 umol/L、153±96 umol/L，引流 后胆红素比引流前下降，差别有统计学意义（P<0.05）；而两组在术中出血量、胆汁细菌感染率、术 后并发症等差别无统计学差异。结论  术前 PTBD 对于黄疸较严重的肝门部胆管癌患者，能有效 的减轻黄疸，是一种安全可行的办法，能有效改善肝功能，增强患者体质，增加手术耐受力。

关键词: PTBD, 疗效与安全性 , 手术, 肝门部胆管癌