Abstract: 【Abstract】 Objective〓To investigate the bacterial distribution and drug resistance of urinary tract infection in adolescent patients. Methods〓From July 2014 to July 2015, 44 patients (aged between 18 and 20) with urinary tract infections were assigned as research subjects. Urine specimen were collected in the middle of urination for urine culture. A total of 1382 isolated bacterial colonies were found. The kinds of pathogens responsible for urinary tract infection,bacterial distribution,antimicrobial susceptibility and resistant strains were analyzed. Results〓The causative organisms included gram-positive bacteria 20.12%, 3.04% fungi, Gram-negative bacteria 76.85%. Most of the bacteria were E.faecium and E.faecalis in the detected gram-positive bacteria (76.91%), E.coli and Pseudomonas aeruginosa in the detected gram-negative bacteria(73.54%),Candida parapsilosis and Candida albicans in the detected fungi. Staphylococcus aureus was the highest resistant to Ciprofloxacin, and E.faecium was to ofloxacin, E.faecalis was to clindamycin,E.coli was to ceftriaxone,pseudomonas aeruginosa was to aztreonam,klebsiella pneumoniae was to Ceftriaxone,citrobacter was to Ciprofloxacin. Conclusion〓As for the young bacterial urinary tract infection patients,Gram-negative bacteria was the main drug-resistant pathogens, especially Escherichia coli.

Key words: Bacterial distribution, Adolescent, Resistance analysis, Urinary tract infection

摘要： 【摘要】 目的 探究近一年来深圳光明新区尿路感染青少年患者细菌分布情况和耐药情况。方法将2014年7月到2015年7月就诊光明新区医院的18~20岁尿路感染患者44例作为研究对象,收集中段尿分离培养细菌共得1382株菌落,分析尿路感染细菌的种类、分布和通过药敏试验分析耐药性。结果〓革兰氏阳性菌20.12%,真菌3.04%,革兰氏阴性菌76.85%;屎肠球菌37.41%,近平滑假丝酵母菌38.10%,大肠埃希菌50.47%。金黄色葡萄球菌对环丙沙星耐药性最强,屎肠球菌耐药性最强的为左氧氟沙星,粪肠球菌耐药性最强的为克林霉素,大肠埃希菌耐药性最强的为头孢曲松,铜绿假单胞菌耐药性最强的为氨曲南,肺炎克雷伯菌耐药性最强的为头孢曲松,柠檬酸杆菌耐药性最强的为环丙沙星。结论〓对于18~20的青少年岁的尿路感染患者,革兰氏阴性菌尤其是大肠埃希菌为主产生耐药性较为广泛。

关键词: 细菌分布, 青少年, 耐药分析, 尿路感染