Abstract: 【Abstract】〓Objective〓To explore the distribution characteristics of liver function in anatomy. Methods〓Forty-seven patients who underwent EOB-CE-MRI scans were analyzed. They were classified into three groups according to Child-Pugh classification (CPS): normal liver function (NLF) group (n=19), CPS A group (n=15), CPS B group (n=13). Liver-liver Rate of Enhancement (LLRE) method was adopted. Statistical analysis were performed by relevant software. A paired t-test was used to compare the differences between the central and peripheral zones, the right and left lobes, the right anterior and right posterior segments, and the S2 and S3 segments in three groups. Afterwards,the signal of pre-contrast and post-contrast in hepatobiliary phase were compared respectively in three groups. The P<0.05 indicated a significant difference. Results〓The LLRE between the central and peripheral zones was significantly difference (P<0.001) for patients. There were no statistical differences between left and right lobe as well as the S2 and S3 segments (P>0.05)..The mean value of the average signal had no difference in pre-contrast and had significant difference after contrast among different groups (P<0.05). Conclusion〓The liver function in the center of the liver was higher than peripheral zones. The difference between left and the right lobes as well as the S2 and S3 segments were not apparent. The relative enhancement ratio was significantly different among different groups.

Key words: Magnetic Resonance Imaging, Gd-EOB-DTPA, Relative enhancement ratio, Segmental liver function

摘要： 【摘要】〓目的〓利用肝特异性对比剂探讨肝功能的解剖分布规律。方法〓分析2012年7月~2014年6月期间行肝脏EOB-CE-MRI的47例患者影像学及临床资料,按照Child-Pugh分级(CPS)分为:正常组19例,CPS A级组15例,CPS B级组13例。采用肝脏相对强化率(LLRE)的方法进行测量,比较三组肝中央区与周围区、左叶与右叶、右前段与右后段、S2段与S3段EOB-CE-MRI平扫、肝细胞期肝实质信号以及肝细胞期肝实质相对强化率的差异。结果〓运用LLRE方法三组患者肝中央区与周围区间差异有统计学意义(P<0.001),左叶与右叶间、右前段与右后段、S2段与S3段不存在统计学差异(P>0.05)。全肝平均信号均值平扫各组间无差异,增强之后各组间存在显著性差异,P值均小于0.05。 结论〓肝中央区肝功能储备高于周围区,左右叶及S2、S3段之间肝功能差异不明显,全肝平均相对强化率各组之间显著不同。

关键词: 节段性肝功能