Abstract: 【Abstract】〓Objective〓To evaluate on the effective nursing management and the effect of continuous renal replacement therapy (CRRT) with non-heparinization on the postoperative cerebral hemorrhage patients. Methods〓Fifty-eight patients underwent CRRT treatment were included in th study. Of then, 30 cases admitted from Jan 2012 to Jan 2014 were served as group A, which adding the soak time of the pipe piercing in heparin to 45 min, and using the improved method of flushing pipe with normal saline during the therapy period. Twenty-eight cases from January 2010 to December 2012 were as group B, in whom the routine clinic management of the CRRT without heparin were used. The filter service life and the change in coagulation function and platelet count were compared between two groups. Results〓The service life of filter in group A was longer than that in group B (P<0.05). No bleeding complication happened in all 58 patients. There were no differences in coagulation function and platelet count between two groups. Conclusion〓non-heparin CRRT treatment in postoperative cerebral hemorrhage patients is feasible and is helpful to prolong the filter working life, but need to increase the soaked time of piercing filter and use the improved method of flushing pipe.

Key words: Continuous renal replacement therapy with no heparinization, Nursing, Cerebral hemorrhage

摘要： 【摘要】 目的 讨论脑出血患者术后行无肝素化连续性肾脏替代治疗(CRRT)的有效护理措施和护理效果观察。方法 选择2012年1月至2014年1月30例患者作为A组,采用预冲管路肝素液的浸泡时间增加到45 min,治疗期间采取改良的盐水冲管方法。选2010年1月至2011年12月28例患者作为B组,采用无肝素化CRRT临床常规护理措施。对比两组滤器寿命和患者的凝血功能、血小板变化。结果 A组在滤器使用时间、滤器堵塞被动下机方面优于B组,差异有统计学意义(P<0.05)。两组间凝血功能和血小板计数的差异没有统计学意义。两组例患者均无再出血并发症。结论 脑出血患者术后行无肝素CRRT治疗,增加预冲管路肝素液的浸泡时间和采取改良的盐水冲管方法,有利于延长滤器使用寿命。

关键词: 无肝素化连续性肾脏替代治疗, 护理, 脑出血