Welcome to Visited Lingnan Modern Clinics In Surgery, Today is

Lingnan Modern Clinics in Surgery ›› 2014, Vol. 14 ›› Issue (01): 73-75.DOI: 10.3969/j.issn.1009-976X.2014.01.021

• 论文 • Previous Articles     Next Articles

One case report of pathological complete remission of rectal cancer after neoadjuvant chemotherapy and review of literature

Lv Zejian, Zhang Yuchao, Liu Yeqing, Liu Gaojie, Chen Shuang   

直肠癌新辅助化疗病理完全缓解1例并文献复习

吕泽坚1,4,张育超2,3,柳叶青2,3,刘高杰2,3,陈双1,4   

  1. 1. 中山大学孙逸仙纪念医院
    2. 中山大学附属第二医院
    3. 中山大学附属第二医院
    4. 中山大学孙逸仙纪念医院
  • 通讯作者: 陈双
  • 基金资助:

    上皮-间质转化诱导Treg分化加速结肠癌转移的分子机制研究;KLF5表达丢失促进结肠癌EMT和转移的分子机制研究

Abstract: 【Abstract】 Objective〓To explore the clinical efficacy of neoadjuvant chemotherapy for patients with colorectal cancer. Methods〓The diagnosis and treatment course of one case with advanced rectal cancer undergoing neoadjuvant chemotherapy in the Gastroenterology Department, Sun Yat-sen Memorial Hospital of Sun Yat-sen University was reported,and related literature were reviewed. Results〓After three cycles of neoadjuvant chemotherapy,the postoperative pathological result after surgery suggested pathological complete remission (pCR). Conclusion〓Neoadjuvant chemotherapy is effective for the treatment of patients with advanced colorectal cancer, and it is suitable for patients with advanced colorectal cancer before operation.

Key words: Colorectal cancer, Neoadjuvant chemotherapy, Pathological complete remission (pCR)

摘要: 【摘要】〓目的〓探讨进展期结直肠癌新辅助化疗的临床疗效。方法〓报道中山大学孙逸仙纪念医院胃肠外科收治的1例接受新辅助化疗的进展期直肠癌患者的诊疗经过,并复习相关文献。 结果〓经过3疗程的新辅助化疗,患者术后病理结果提示完全病理缓解(pCR)。结论〓新辅助化疗对进展期结直肠癌患者是有效的,适合在进展期结直肠癌患者术前应用。

关键词: 结直肠癌, 新辅助化疗, 病理完全缓解

CLC Number: