Abstract: Objective To study how to select the most appropriate treatment in treating choledocholithiasis with cholecystolithiasis and its curative effect. Methods Clinical data of 52 patients with choledocholithiasis and cholecystolithiasis in our hospital from October 2010 to October 2011 were retrospectively analyzed .Through the different treatment methods we analyzed the effect and safety . Results In this group of 52 patients ,24 patients were treated by LC+LCBDE, 2 of them converted to laparotomy. 25 patients were treated by EST+LC; 3 patients were treated by ENBD+LC+LCBDE. None of the 52 patients appeared the complication of bile leakage, bleeding, pancreatitis, cholangitis or residual stones . Conclusion Selecting the optimal combination of the three endoscopes after examinations to deal with the disease has concentrated the superior of the three endoscopes . It's the least traumatic way to treat the disease , the effect is positive.

摘要： 目的：探讨胆囊结石合并胆总管结石治疗中如何选择最恰当的方法及其疗效。方法：回顾性分析我院2010年10月至2011年10月期间收治的胆囊结石合并胆总管结石患者共52例，通过不同的治疗方法分析手术疗效及安全性。结果：52例患者中，通过LC+LCBDE方案治疗24例，中转开腹2例；EST+LC方案治疗25例；ENBD+LC+LCBDE方案治疗3例。52例术后均未出现胆漏，出血，胰腺炎，胆管炎及残留结石等并发症。结论：胆囊结石合并胆总管结石患者根据术前检查选择三镜最优组合集中了三种治疗手段的优势，是目前治疗该病创伤最小的方法，疗效是肯定的。

关键词: 腹腔镜, 十二指肠镜, 胆道镜, 胆总管结石, 胆囊结石