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Lingnan Modern Clinics in Surgery ›› 2012, Vol. 12 ›› Issue (01): 13-15.

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腹膜后自体脾移植治疗外伤性脾破裂的前瞻性研究

  

腹膜后自体脾移植治疗外伤性脾破裂的前瞻性研究

曾宪成1,李文宏2,何文广1,3,刘其龙1,3,苏安1,3,黄延年1,3   

  1. 1. 中山大学附属博济医院(增城市人民医院)
    2. 中山大学附属博济医院普外科
    3.
  • 通讯作者: 曾宪成
  • 基金资助:
    广东省科技计划项目

Abstract: Objective To study clinical feasibility and value of retroperitoneal splenic autotransplantation in severe trauma of the spleen. Methods A prospective case-control study, the retroperitoneal splenic autotransplantation, the omentum of splenic autotransplantation were performed in 32 and 34 cases respectively.The spleen-preserving operations were observation of postoperative general condition, after 1 day to 12 months of blood routine, blood IgA, IgM, IgG, C3, Tuftsin level changes. Results Retroperitoneal splenic autotransplantation group operation time is shorter than that in omentum of splenic autotransplantation group ( P< 0.05 ). 1 cases of postoperative adhesive obstruction in the omentum of splenic transplantation group,other general condition, after 1 day to 12 months of blood IgA, IgM, IgG, C3, Tuftsin levels showed no significant difference ( P> 0.05 ) in two groups. Conclusion Retroperitoneal splenic autotransplantation to retain part of spleen immune function, and the operation is relatively simple.It’s a deserved popularized method.

Key words: Splenic injury, Spleen transplantation, Retroperitoneal

摘要: 目的 探讨腹膜后自体脾移植在严重脾外伤保脾手术中应用的可行性及价值。方法 采用前瞻性病例对照研究,将66例严重脾外伤病人分为腹膜后自体脾移植组例、大网膜自体脾移植组,其中腹膜后自体脾移植组32例,大网膜自体脾移植组34例。观察术后一般情况,术后1天~ 12个月血常规,血IgA、IgM、IgG、C3、Tuftsin水平变化。结果 腹膜后自体脾移植组手术时间短于大网膜自体脾移植组(P<0.05),术后其它一般情况变化、术后1天~ 12个月血IgA、IgM、IgG、C3、Tuftsin水平两组无统计学差异(P> 0.05)。结论 腹膜后自体带蒂脾移植术能够保留脾脏的部分免疫功能,且手术操作简便,在临床上推广应用是可行的。

关键词: 脾外伤, 脾移植, 腹膜后

CLC Number: