Analysis of the characteristics and risk factors of chronic lower extremity venous diseases in diabetes

doi:10.3969/j.issn.1009-976X.2023.01.007

Abstract

Abstract: Objective To observe the clinical characteristics of diabetic patients with venous disease （VD）. Methods A total of 44 VD patients with （DM group） or without （NC group） diabetes hospitalized in the department of vascular surgery, Sun Yat-sen Memorial hospital, Sun Yat-sen University from September 2018 to January 2019 were enrolled in this study, and the clinical manifestations of VD patients in these two groups were compared. The patients were further divided into 4 groups according to the degree of VD. The baseline data of each group were compared, and the orderly multivariate logistic regression was conducted to analysis the risk factors related to the severity of VD. Results DM Patients presented to have more severe VD. The complication of DM and high level of creatine kinase isoenzyme （CM-KB） were clarified to be risk factors related to the severity of venous lesions. Conclusion Patients with diabetes presented to have more severe venous lesions than those without; the combination of DM and high level of CK-MB are evaluation factors for the high risk of exacerbation of chronic venous disease.

Key words: diabetes mellitus, chronic venous disease, CK-MB

摘要： 目的观察糖尿病静脉病变患者的临床特点,探讨与慢性静脉疾病病情加重相关的危险因素。方法收集 2018年9月至2019年1月于中山大学孙逸仙纪念医院血管外科住院的合并糖尿病（DM组）或非合并糖尿病（NC组）的慢性下肢静脉疾病患者共44例,对比两组患者的静脉病变临床表现。按静脉病变程度将患者分为4组,对比各组间基线资料,采用有序多分类Logistic回归分析与慢性下肢静脉疾病加重相关的危险因素。结果糖尿病患者的静脉病变较非糖尿病患者更为严重;合并糖尿病和高水平肌酸激酶同工酶（CM-KB）是慢性静脉病变加重的风险因素。结论糖尿病患者的慢性静脉疾病较非糖尿病患者更严重;合并糖尿病、高水平CK-MB可以作为慢性静脉疾病加重高风险的评估因素。

关键词: 糖尿病, 慢性下肢静脉疾病, CK-MB

CLC Number:

R654.3

ZHU Tian-xin, CHEN Hong-xing, HUANG Kai, YOU Li-li, YANG Chuan, LIU Dan, YAN Li, REN Meng. Analysis of the characteristics and risk factors of chronic lower extremity venous diseases in diabetes[J]. Lingnan Modern Clinics In Surgery, 2023, 23(01): 35-41.

朱天欣, 陈红星, 黄楷, 尤丽丽, 杨川, 刘丹, 严励, 任萌. 糖尿病慢性下肢静脉病变特点及其风险因素分析[J]. 岭南现代临床外科, 2023, 23(01): 35-41.

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