Abstract: Objective To study the clinical effect of barbed suture in laparoscopic repair of perforation of gastroduodenal ulcer. Methods Eighty patients undergoing laparoscopic repair of gastroduodenal ulcer perforation were divided into two groups with forty patients in each group. The observation group was sutured with barbed wire in management of gastroduodenal perforationduring operation, while the control group was sutured with ordinary Microjoe wire. To compare the suture time, operation time, anal recovery time,in hospital time and Incidence of complications in two groups. Results The suture time and operative time of the observation group were （6.64±1.15）min and （37.15±3.49）min, and that of the control group were （9.53±1.28）min and （42.40±3.34）min, which were shorter than that of the control group （P<0.05）. The anal recovery time and in hospital time of the observation group were （39.58±4.78）h and （8.08±0.92）d, and that of the control group were （40.66±4.25）h and （8.35±0.98）d, there were no significant difference between the two groups （P>0.05）. Postoperative pulmonary infection occurred in 4 cases in the observation group and 5 cases in the control group, and the difference between the two groups was not statistically significant （P>0.05）. Conclusion The use of barbs in laparoscopic gastroduodenal perforation repair can shorten the suture time and operation time, is a feasible technology.

Key words: laparoscope, repair of peptic ulcer perforation, barbedsuture, clinical effect

摘要： 目的 探讨倒刺缝线在腹腔镜胃十二指肠溃疡急性穿孔中的应用效果。方法 80例行腹腔镜胃十二指肠溃疡穿孔修补术患者分为2组,每组各40例,观察组术中使用倒刺线缝合,对照组使用普通微乔线缝合。比较两组患者缝合时间、手术时间、肛门恢复排气时间及住院时间,并发症的发生率。结果 观察组缝合时间（6.64±1.15）min,对照组缝合时间为（9.53±1.28）min,观察组短于对照组（P<0.05）,观察组手术时间为（37.15±3.49）min,而对照组为（42.40±3.34）min,观察组短于对照组（P<0.05）。观察组、对照组肛门恢复排气时间分别为（39.58±4.78）h、（40.66±4.25）h,两组差异无统计学意义（P>0.05）。观察组对照组住院时间分别为（8.08±0.92）d、（8.35±0.98）d,两组差异无统计学意义（P>0.05）。观察组术后4例并发肺部感染,对照组为6例,两组差异无统计学意义（P>0.05）。结论 腹腔镜胃十二指肠穿孔修补术中使用倒刺缝线能够缩短缝合时间和手术时间,是一种可行的技术。

关键词: 腹腔镜, 消化性溃疡穿孔修补术, 倒刺缝线, 临床效果