Analysis of risk factor between asymptomatic carotid intraplaque hemorrhage and cerebral infarction and death after coronary stent implantation

doi:10.3969/j.issn.1009-976X.2020.03.023

Abstract

Abstract: Objective To investigate risk factors for postoperative ipsilateral cerebral infarction and all-cause mortality after coronary stent implantation in patients with asymptomatic carotid artery stenosis （ACS）. Methods 110 patients with carotid stenosis of 50% or more were included in the study. The relationship including carotid intraplaque hemorrhage （IPH）, ipsilateral cerebral infarction and all-cause mortality was analyzed retrospectively. Results Sixteen cases of IPH occurred in 110 ACS patients（14.5%）. Six cases of IPH （37.5%） and 6 cases （6.4%） encountered ipsilateral infarction and all-cause mortality, respectively. Multivariate Cox regression analysis showed that IPH was a predictor of ipsilateral cerebral infarction （HR：18.47,95%CI： 5.14~76.08,P<0.001）and all-cause mortality and all-cause mortality （HR：4.26, 95%CI： 1.48~11.76, P=0.016）. Conclusion In patients with ACS undergoing coronary stent implantation, IPH is associated with a high risk of postoperative cerebral infarction and all-cause mortality.

Key words: asymptomatic carotid artery stenosis, all-cause mortality, cerebral infarction

摘要： 目的探讨无症状颈动脉狭窄（ACS）患者冠状动脉支架植入手术后并发脑梗塞和死亡的危险因素。方法 110例颈动脉面积狭窄达50%或以上的患者被纳入研究。回顾性分析术前颈动脉粥样硬化斑块内出血（IPH）等因素与术后同侧脑梗塞及死亡率的关系。结果 110例ACS患者中共发生16例IPH（14.5%）,其中有6例IPH（37.5%）和6例（6.4%）分别发生同侧脑梗塞和全因死亡。多变量Cox回归分析显示IPH是同侧脑梗塞和全因死亡率的预测因素（HR：18.47,95%CI：5.14~76.08,P<0.001）和全因死亡率（HR：4.26,95%CI：1.48~11.76,P=0.016）。结论在接受冠状动脉支架植入手术的ACS患者中,IPH与术后脑梗塞和全因死亡率的高风险密切相关。

关键词: 脑梗塞, 无症状颈动脉狭窄, 死亡率

CLC Number:

R651.1

LI Wan-chun, GAO Yan-sheng. Analysis of risk factor between asymptomatic carotid intraplaque hemorrhage and cerebral infarction and death after coronary stent implantation[J]. Lingnan Modern Clinics in Surgery, 2020, 20(03): 367-370.

李万春, 高岩升. 无症状颈动脉粥样硬化斑块内出血与冠状动脉支架植入手术后脑梗塞和死亡的分析[J]. 岭南现代临床外科, 2020, 20(03): 367-370.

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