Abstract: Infective endocarditis is a serious，life threatening cardiovascular diseases. Early diagnosis and early surgical treatment are the key to treating infective endocarditis. Appropriate early surgery can avoid death and severe complications，but the best time for surgery remains unclear. The benefits of early surgery should be weighed against its risks by Multidisciplinary collaborations for the clinical worker ，to ensure the opportunity of early surgery for patients. Currently，the main indications for early surgery in patients with IE are heart failure，uncontrolled infection and prevention of embolism. Here we discuss the diagnosis of infective endocarditis，antibiotic treatment and surgical indications.

Key words: infective endocarditis, antibiotic treatment, surgical indications, diagnosis

摘要： 感染性心内膜炎是一种严重威及生命的心血管疾病。早期明确诊断、早期手术治疗是治疗感染性心内膜炎的关键。适当的早期手术可以避免死亡和严重并发症，但手术的最佳时机仍不清楚。这需要临床工作者通过多学科合作来对早期手术的益处与风险进行权衡，以确保为患者提供早期手术的机会。目前，感染性心内膜炎早期手术治疗的主要适应症是：心力衰竭、不受控制的感染和预防栓塞。在这里，我们就感染性心内膜炎的诊断、抗菌治疗和手术治疗的适应症展开讨论。

关键词: 感染性心内膜炎, 抗菌治疗, 手术适应症, 诊断