Abstract:

Objective To compare the sonographic and mammographic features in patients with ductal carcinoma in situ（DCIS）and DCIS with microinvasion（DCISM）. Methods A total of 147 women （94 DCIS and 53 DCISM） were retrospectively included. The sonographic lesions were classified as either masses or non-mass abnormalities. The lesions on mammography were classified as calcifications only, mass, asymmetry or architectural distortion. Statistical comparisons were made using Mann?Whitney U test, χ2 test, Fisher′s exact test and multiple logistic regression analysis. Results Univariate and multivariate analyses showed that the presence of microcalcifications and vascularity on sonography were associated with DCISM（P=0.038, P=0.025）. Moreover, a greater range of calcification distribution were associated with a higher likelihood of DCISM（P=0.002）. Conclusion The presence of microcal-cifications and vascularity on sonography or a great range of microcalcification distribution on mammo-graphy may suggest DCISM.

Key words: sonography, breast ductal carcinoma in situ, mammography, microinvasion

摘要：

目的　比较导管原位癌（DCIS）及导管原位癌伴微浸润（DCISM）超声及X线特征的差异。方法　经手术病理诊断为DCIS和DCISM的病例共147例（DCIS94例，DCISM53例）。超声上，病变分为肿块及非肿块。X线上，病变分为单纯钙化、肿块、局灶不对称或结构扭曲。统计分析采用χ2检验，Fisher确切概率法及多因素logistic回归分析。结果　单因素及多因素分析结果显示，超声上病变内可见钙化及血流提示DCISM可能（P=0.038，P=0.025）。此外，X线上钙化范围越大,DCISM可能性越高（P=0.002）。结论　与DCIS相比,超声上病变内可见钙化及血流、X线上钙化分布范围较大与DCISM相关。

关键词: 微浸润, 超声, 乳腺X线摄影, 导管原位癌