Abstract: ［Abstract］ Objective To investigate the association between smoking and lesion sites of colorectal cancer in male patients. Methods Clinical data of male patients with colorectal cancer who were admitted into our hospital from 2010 to 2016 were collected and retrospectively analyzed. Patients were divided into smoking group and non?smoking group. Results There were significant differences in the age composition ratio between left?and right?sided colon cancer smoking and non?smoking group（P<0.05）. More patients with left?sided colon cancer in non?smoking group suffered from hematochezia（35.4%）, while abdominal pain seems more common in the smoking group（33.0%）（P<0.05）. The proportion of patients with high differentiation adenocarcinoma in smoking group was higher than that in non?smoking group（P<0.05）；when it comes to the smoking index, the proportion of heavy smokers in rectal cancer were higher than the right?and left?sided colon cancer patients （P<0.05）. Conclusion Smoking and location are independent factors for colorectal cancer, different parts of colorectal cancer between smoking and non?smoking groups have differences in the diagnosis of sensitivity, clinical pathology and prognosis.

Key words: male, colorectal cancer, location, smoking

摘要： ［摘要］目的 研究吸烟与男性大肠癌人群发病部位的关联。方法 收集我院2010~2016年的男性结直肠癌住院患者，按吸烟变量和发病部位分组，进行回顾性病例分析。结果 右半结肠癌、直肠癌吸烟与不吸烟组在年龄构成上有差别（P<0.05）；左半结肠癌便血更多见于非吸烟组（35.4%），腹痛更多见于吸烟组（33.0%）（P<0.05）；吸烟组高中分化腺癌患者比例高于非吸烟组（P<0.05）；在吸烟指数上，直肠癌重度吸烟者依次高于右半结肠癌、左半结肠癌患者相应比例（P<0.05）。结论 吸烟和发病部位分别是影响大肠癌发病的独立因素，不同部位吸烟与不吸烟男性肠癌患者在肿瘤的诊断、临床病理学特征、预后等方面存在差异。

关键词: 肠癌, 吸烟, 部位, 男性