Abstract: 【Abstract】〓Objective〓To evaluate the value of dynamic detection of procalcitonin (PCT) in early diagnosis of infection after minimally invasive esophagectomy. Methods〓Sixty-eight patients as a observation group who underwent minimally invasive esophagectomy in department of cerebral surgery of Sun Yat-sen Memorial Hospital between June 2015 to June 2016 and 30 cases of normal physical examination as healthy group over the same period were enrolled in this retrospective study. PCT in blood of the patients undergoing surgery were detected on the first, second, third and fifth day after the surgery. Infection occurred in 10 patients out of the group, which were divided into an observation group and the others were divided into a control group. Differences of PCT among the three groups were statistically analyzed using SPSS 12.0 software package. Results〓On the first day after operation, PCT in the observation group and control group was higher than the healthy group,.which showed statistical difference(P<0.05),.but it has no statistical difference between observation group and control group..On the second day,.the PCT of the observation group was higher than control group, which showed statistical difference(P<0.05)..And on the third and the fifth day,.the PCT of the observation group was higher significantly than control group, which showed statistical difference (P<0.01)..Between the control group and healthy group,.there was statistical difference on the first and second day after operation(P<0.05), but it has no statistical difference on the third and fifth day after operation..Conclusion〓A dynamic detection of PCT is value to the early diagnosis of infection after minimally invasive esophagectomy..When PCT is more than 2.06 μg/ml on the second day after operation, the patient may be infected by bacteria. We should start the contrapuntal treatment as early as possible.

Key words: Infection, Dynamic detection, Minimally invasive esophagectomy, Procalcitonin

摘要： 【摘要】 目的 评价动态检测降钙素原对食管癌微创术后感染的早期诊断价值。方法〓选择我院胸外科2015年6月至2016年6月食管癌微创手术患者68例为观察对象(观察组),同期健康体检患者30例为健康组;分别检测实验组术后第1、2、3、5天的静脉血PCT值,其中10例发生感染,归为感染组,余58例为未感染组。比较感染组、未感染组及健康组三组的PCT值。结果〓术后第1天感染组、未感染组PCT较健康组升高(P<0.05),感染组和未感染组无统计学差异;术后第2天感染组较未感染组PCT升高(P<0.05),术后第3天及第5天感染组较未感染组PCT有显著升高(P<0.01),术后前两天未感染组较健康组升高有显著统计学差异(P<0.05),第3及第5天无明显统计学差异。结论〓动态检测降钙素原对食管癌微创术后合并感染有早期诊断价值,术后第2天PCT≥2.06 μg/mL时警示有可能合并细菌感染,可尽早开始针对性地抗感染治疗。

关键词: 感染, 降钙素原, 食管癌微创手术, 动态检测