Abstract:

【Abstract】〓Objective〓To explore short-term outcomes and prognosis of laparoscopic versus open resection for colorectal cancer in elderly patients. Methods〓The clinicopathological and follow-up data of elderly patients with colorectal cancer in the No.1 People's Hospital of Guangzhou from Jun..2003 to Dec..2013 were analyzed retrospectively,.and operative and oncological outcomes were compared respectively between two groups. Results〓A total of 104 patients were included in the study. Sixty-three patients underwent laparoscopic surgery,.whereas 41 underwent open surgery..There were no statistically significant differences of baseline data and follow up period between laparoscopic surgery and open surgery group..Compared with the open surgery group,.the laparoscopic surgery group showed significantly less blood loss,.postoperative activity time,.earlier resumption of an oral diet..No significant differences were observed in overall mortality, cancer-related mortality and recurrence rate. As survival analysis showed,.there were no significant differences in cumulative overall survival, cancer-related survival and recurrence-free rates. Conclusion Laparoscopic surgery in elderly colorectal cancer patients is superior to open surgery in terms of short-term outcomes and not inferior to open surgery in terms of overall survival.

Key words: Colorectal cancer, Open surgery, Laparoscopic surgery, Elderly patients, Prognosis

摘要：

【摘要】 目的 探讨腹腔镜及开腹手术治疗老年结直肠癌病人的短期结果及预后。方法〓回顾性分析2003年1月至2013年12月广州市第一人民医院胃肠外科收治的行腹腔镜或开腹手术结直肠癌病人的临床、病理资料及随访数据。对两组病人的手术学指标、肿瘤学指标及生存情况进行比较。结果〓从数据库中提取符合上述条件的病人共104例,腔镜手术组63例,开腹手术组41例,腹腔镜组和开腹组病人的基线数据及随访时间差异无统计学意义。腹腔镜组病人术中出血量、首次下床活动时间、首次进食流质时间明显低于开腹组,差异有统计学意义。两组病人总死亡率、肿瘤相关死亡率及复发率差异无统计学意义,生存分析显示两组病人累积总生存率、肿瘤相关生存率及累积无复发率差异无统计学意义。结论〓对于老年结直肠癌病人,腹腔镜手术可以取得优于开腹手术的短期结果及不劣于开腹手术的长期生存结果。

关键词: 老年, 腹腔镜手术, 预后, 开腹手术, 结直肠癌