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Lingnan Modern Clinics in Surgery ›› 2016, Vol. 16 ›› Issue (03): 337-340.DOI: 10.3969/j.issn.1009-976X.2016.03.025

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Comparison study of preoperative antibiotic use on minimally invasive percutaneous nephrolithotomy for treatment of staghorn stone

ENG Peng, JIANG Chonghe, CHEN Shaojuan, PAN Chuzao, ZENG Jianwen, MO Jianfeng, ZENG Shaohua   

经皮肾镜取石术治疗鹿角形结石术前抗生素使用的对比研究

曾鹏 蒋重和 陈少娟 潘楚灶 曾健文 莫鉴锋 曾少华   

  1. 广州医科大学附属第六医院(清远市人民医院)
  • 通讯作者: 曾鹏
  • 基金资助:

    广东省清远市科技计划项目

Abstract: 【Abstract】〓Objective〓To investigate the effectivity and strategy of preoperative antibiotic use in treatment of staghorn calculi by percutaneous nephrolithotomy (PCNL). Methods〓Ninety-six patents who suffered from kidney staghorn calculi with no urinary tract infection were selected PCNL procedure. The patients were divided into two groups, Group A(n=49), preventive antibiotics administrated 1 hour before the operation, Group B (n=47), received cephalosporin treatment for 3 days before the operation. The incidence of bacteriuria and fever after the operation were compared. Results〓The surgical procedure of PCNL was completed in allpatients. The incidence of bacteriuria was 18.4%, fever 26.5% in group A, while the incidence of bacteriuria was 4.3%, postoperative fever 10.6% in group B. The incidence of bacteriuria and fever after the operation were lower in patients treated with cephalosporin 3 days before the operation than the patients with preventive treatment (P<0.05). Conclusion〓The management of preoperative antibiotics treatment for 3 days in the patient with kidney staghorn calculi but no clinical and laboratory infection evidence efficiently reduced the incidence of postoperative bacteriuria and fever after PCNL.

Key words: Treatment, Kidney stone, Percutaneous nephrolithotomy, Staghorn calculi

摘要: 【摘要】 目的 探讨经皮肾镜取石术(PCNL)治疗鹿角形结石术前抗生素的使用,预防术后感染。方法〓选择96例无合并泌尿系感染的鹿角形肾结石拟行PCNL术的患者,分成两组,预防性用药组术前1小时给予抗生素,治疗性用药组术前予以头孢菌素治疗3天,对比术后菌尿、发热的发生率。结果〓预防性用药组49例,术后菌尿发生率18.4%,术后发热发生率26.5%;治疗性用药组47例,术后菌尿发生率4.3%,术后发热发生率10.6%,均低于预防性用药组(P<0.05)。结论〓对于无临床及实验室感染证据的鹿角形结石患者行PCNL术前应用抗生素3天,可有效降低术后菌尿及发热的发生率。

关键词: 肾结石, 鹿角形结石, 经皮肾镜取石术, 治疗

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