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Lingnan Modern Clinics in Surgery ›› 2016, Vol. 16 ›› Issue (01): 115-118.DOI: 10.3969/j.issn.1009-976X.2016.01.030

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The development of medical adhesive for vascular anastomosis and repair

HOU Biao, XIE Songlin   

医用粘合剂在血管吻合及修复中应用的研究进展

侯彪 谢松林   

  1. 南华大学附属南华医院
  • 通讯作者: 侯彪

Abstract: 【Abstract】 Vascular anastomosis is the cornerstone of vascular, microsurgery, cardiovascular and transplant surgery. The quality of anastomosis determines the success of the whole surgery. The main aim of performing a vascular anastomosis is to achieve maximal patency rates. An important factor to achieve that goal is to minimize damage to the vessel walls. In recent years, many new methods of vascular anastomosis and materials are being reported, and the utilize of medical adhesives in vascular anastomosis and vascular repair has certain advantages.Because of no permeability damage of vessel wall,small effect of anastomosis haemodynamics,endothelialization are more easily to complete. Compared to other methods of vascular anastomosis,using medical adhesives in vascular anastomosis and vascular repair can shorten the operation time,reduce perioperative bleeding,has better histocompatibility.According to its source,bonding mechanism,clinical application and research progress, the present article make a brief review.

Key words: Medicinal adhesive, Fibrinogen, Vascular Surgery, Photochemical tissue bonding, Cyanoacrylate, Vascular repair

摘要: 【摘要】〓血管吻合术是血管外科、显微外科、心血管外科、器官移植手术的基石,血管吻合的质量关系到整个手术的成败。血管吻合及修复的主要目标是使吻合或修复血管获得最大的近期和远期通畅率,最大化的减少对血管壁的损伤则是提高血管通畅率的重要手段。近年来,新的血管吻合方法和吻合材料不断得到报道,其中利用医用粘合剂行血管吻合术血管修复具有一定优势,对血管壁无透壁性损伤,吻合口局部血流动力学影响小,内皮化更易完成。相对于其他血管吻合方法,医用粘合剂行血管吻合或修复能缩短手术时间、减少围手术期出血、具有更好的组织相容性。本文根据其来源、粘合机制、临床运用、研究进展做一简要综述。

关键词: 血管吻合, 光敏组织化学粘合剂, 医用粘合剂, 血管外科, 纤维蛋白原, 氰基丙烯酸酯

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