Abstract: 【Abstract】〓With the development of oncotherapy technology, intraperitoneal hyperthermic perfusion chemotherapy (IHPC) has increasingly become the preferred treatment modality for abdominal tumor in many medical centers of the world. The advantage of IHPC, both chemotherapy and intraperitoneal perfusion therapy, has been accepted in medical field gradually. Combining IHPC with cytoreductive surgery has a good therapeutic effect on abdominal tumor. Here, we aim to review the state of research on IHPC chemotherapy about development history, mechanism, clinical effect, and discuss the related problems.

Key words: Intraperitoneal hyperthermia perfusion chemotherapy, Tumor, Mechanism

摘要： 【摘要】〓随着对腹腔肿瘤的治疗技术不断发展,世界上众多医疗中心已经把腹腔热灌注化疗作为治疗腹腔肿瘤的治疗方式。腹腔热灌注化疗对治疗腹腔内肿瘤的优势已经逐渐为医学界所认同。其兼有化疗和腹腔灌注疗法的优点,并且能使两者相互协同。把腹腔热灌注化疗和减瘤术结合起来对腹腔肿瘤有良好疗效。本文就近年来有关IHPC的发展历史、治疗作用机制,临床应用及疗效等方面进行探讨,旨在阐明腹腔热灌注化疗的研究现状及存在问题。

关键词: 腹腔热灌注化疗｜肿瘤｜作用机制