Abstract:

【Abstract】〓Objective〓To compare the diagnostic agreement of ultrasound and mammography for detection of microcalcification in breast cancer and to investigate the factors that influence on diagnostic accuracy of ultrasound. Methods〓Eighty-seven patients with breast cancer underwent both ultrasound and mammography. Characteristics of breast lesions and microcalcifications were analyzed. The diagnostic consistency and influential factors in detection microcalcifications were also compared. Results〓Detection rate and accurate diagnosis of malignancy in ultrasound were higher than inmammography (χ2=9.911, P=0.002). No statistically significant difference was found for detection of microcalcifications between ultrasound and mammography (P>0.05), and higher consistency was found between them (k=0.652). Compared with mammography that was regarded as the standard in detection of microcalcifications, ultrasound had a sensitivity of 82.1%, a specificity of 83.3%, a false positive rate of 16.7%, afalse negative rate of 17.9% for detecting microcalcifications. The size and cluster of the microcalcifications in mammography in fluenced the detection of microcalcifications with ultrasound (P<0.05). Conclusion〓Ultrasound is more sensitive than mammography in detection and diagnosis of breast malignancy. Ultrasound is effective to detect microcalcificationsin breast cancer, but is influenced by the size and cluster of microcalcifications.

Key words: Breast cancer, Microcalcifications, Ultrasound, Mammography

摘要：

【摘要】〓目的〓比较超声与钼靶X线摄影检测乳腺癌微小钙化的一致性,探讨影响超声检测乳腺癌微小钙化的影响因素。方法〓87例乳腺癌行超声及钼靶X线摄影检查,分析二者的乳腺病灶及微小钙化的特点,比较二者检测的一致性,分析超声检测微小钙化的影响因素。结果〓超声对病灶的显示率及诊断恶性的准确率均高于钼靶(χ2=9.911,P=0.002)。二者在微小钙化的检出方面无统计学差异(P>0.05),具有较高的一致性(k=0.652)。以钼靶显示微小钙化作为标准,超声检测微小钙化的敏感度为82.1%,特异度为83.3%,假阳性率16.7%,假阴性率为17.9%。钼靶上微小钙化的大小及密集程度影响其超声检测(P<0.05)。结论〓超声较钼靶X线摄影能更敏感地检测及诊断乳腺恶性病变;超声能有效地检测乳腺癌微小钙化,但易受微小钙化的大小及密集程度的影响。

关键词: 乳腺癌, 微小钙化, 超声检查, 钼靶