Abstract: 【Abstract】〓Objective〓To explore the clinical characteristics of biliary cystadenoma (BCA) and review literature. Methods〓Six cases with BCA were admitted to Sun Yat-sen Memorial Hospital from September 2009 to September 2014 and underwent surgical procedure. The Clinical manifestation, imaging feature and surgical results from six BCAs were analyzed retrospectively. Results〓All 6 patients were female, and aged from 28 to 46 years old. Chief complains were upper abdominal pain (50%, 3/6), asymptomatic examination found (33.3%,..2/6) and jaundice with fever(13.7%,..1/6). Course of disease ranged from 3 days to 16 years. No abnormal preoperative liver functions were found except the cases with jaundice and fever,..and tumor markers of all the patients showed no abnormality. Preoperative B ultrasound,..and CT examinations failed to make an accurate diagnosis, only two case were confirmed by MR...All patients underwent complete resection of the whole lesion without complication or recurrence in a follow-up duration of 3-46 months. Conclusion〓The incidence of BCA is rare and its cause is unclear. It occurs predominantly in middle-aged women with mild clinical symptoms and it is hard to make an accurate preoperative diagnosis by laboratory and imaging examinations. The final diagnosis still depends on pathological examination. Complete removal of the whole lesion is essential for BCA.

Key words: Biliary tumors, Cystadenoma, Diagnosis, Treatment

摘要： 【摘要】〓目的〓分析6例胆管囊腺瘤的临床特点,提高对胆管囊腺瘤的认识。方法〓回顾性分析中山大学孙逸仙纪念医院自2009年9月到2014年9月收治的6例胆管囊腺瘤患者的临床表现、影像特点及手术治疗结局情况。结果〓6例患者均为女性,年龄28~46岁。就诊主诉为:上腹痛占50%(3/6),无症状体检发现33.3%(2/6),黄疸、发热占13.7%(1/6)。发病至就诊时间3天~16年。除黄疸、发热患者肝功能异常外,其余患者术前肝功能无异常。肿瘤指标均无异常。术前B超、CT均未能作出准确定性诊断,仅2例术前经MR检查准确诊断。全部患者均行外科手术完整切除病灶,术后无明显手术并发症。术后随访3月~46月无复发。结论〓胆管囊腺瘤发病稀少,病因未明,好发于中年女性,临床症状轻,实验室及影像学检查诊断本病有一定困难,目前仍然依赖于病理。本病手术效果良好,完整切除病灶对本病预后极为重要。

关键词: 胆管肿瘤, 囊腺瘤, 诊断, 治疗