Abstract: 【Abstract】〓Objective〓To investigate the method to repair severe radiation-induced ulceration and evaluate its clinical effects. Methods〓Twenty-two cases with severe radiation-induced ulceration treated by flaps or musculocutaneous flaps transfer in our hospital from Jan 2010 to Jan 2012 were respectively analyzed. Of 22 case, 4 cases were treated by latissimus dorsa flaps, 3 cases by lateral abdominal flap, 3 cases by paraumbilical flap, 4 cases by anterolateral femoral flaps ,6 cases by pectoralis majorflap, 2 cases by gluteus maximus muscle flap. Results〓20 cases flaps survived with primary healing, 2 cases flap with partial distal necrosis. The colour and texture of the flaps were excellent,and the outline and functional results were satisfactory after 1 to 2 years follow-up..There was no ulcer recurrence. Conclusion〓The efficacy of cervical radiation induced ulceration by flaps and musculocutaneous flaps was proved. The reconstruction could prevent the recurrence of ulcer.

Key words: Radiation ulcer, Skin flap, Implantation

摘要： 【摘要】〓目的〓使用皮瓣或肌皮瓣对严重放射性溃疡进行修复的临床经验。方法〓对我科在2010年1月至2012年1月,采用各种皮瓣或肌皮瓣方法修复治疗的22例放射溃疡患者病例进行回顾性分析,其中使用背阔肌皮瓣4例,侧腹壁皮瓣3例,脐旁皮瓣3例,股前外侧皮瓣4例,胸大肌皮瓣6例,臀大肌皮瓣2例。 结果〓22例患者中有2例出现了皮瓣远端局部坏死,经换药治疗后创面闭合。其他20例皮瓣全部成活,伤口一期愈合。经1~2年随访,15例患者皮瓣外观良好,质地柔软,临床溃疡无复发。结论〓临床采用皮瓣或者肌皮瓣治疗严重放射性溃疡,能够获得良好治疗效果,并能有效预防溃疡复发,值得推广。

关键词: 放射性溃疡, 皮瓣, 移植