关键词: 危险因素, 尿结石成分, 原发性高血压, 相关性

Abstract: ［Abstract］ Objective To observe the risk factors of renal calculi in patients with primary hypertension and analyze the correlation between primary hypertension and stone compositions. Methods 685 cases of renal calculi patients treated in our hospital from August 2015 to December 2017 were grouped with（group A）or without（group B）primary hypertension. Sex, age, BMI and blood biochemical indexes were counted, screening the related risk factors. The lithiasis composition of stone specimens was analyzed by infrared spectroscopy. The statistical analysis was carried out by SPSS software such as t test, Chi square test and Pearson correlation analysis. Results 372（54.3%）patients （group A）with primary hypertension had higher BMI, blood uric acid, fasting blood glucose, triglyceride, blood urea nitrogen and blood creatinine and lower blood albumin level, when compared with 313（45.7%）without hypertension （P<0.05）. The stone composition in group A included calcium oxalate （32.97%） and uric acid（23.78%）, and calcium carbonate stone, calcium phosphate stone, magnesium phosphate stone were significantly reduced than that in group B. There were positive correlations between different grades of hypertension and renal stone components（χ2=27.57, P=0.016；r=0.100）and between uric acid stones and hypertension grade（r=0.270, P<0.05）. Conclusion Hypertension, hyperuricacid, hyperglycemia, hypertriglyceridemia, hypoproteinemia, elevated blood urea nitrogen and creatinine are risk factors for kidney stones. There is a certain correlation between the classification of hypertension and the composition of urinary calculus.

Key words: correlation, urinary stone composition, primary hypertension, risk factors