关键词: 镇静, 临床护理, 右美托咪定, 无痛胃镜

Abstract: ［Abstract］ Objective To investigate the sedative and analgesic effect and safety of dexmedetomidine in painless gastroscopy. Methods Sixty patients who underwent painless gastroscopy were enrolled in the observation group and the control group. The former was pumped with dexmedetomidine 0.1 mg/kg and the latter with propofol 1.5 mg/kg. The vital signs，sleep，intraoperative operation，waking time and Ramsay score were used to observe and record the sedative and analgesic effects in two groups of patients during gastroscopy. Results The sleep，operation time and awaking time in observation group were shorter than that in control group. The Ramsay score of the observation group was higher than that of the control group（P<0.05）. The differences of vital signs between two groups were not statistically important（P>0.05）. Conclusion Dexmedetomidines in painless gastroscopy is a reliable and safe in sedation andanalgesia，and the vital signs are stable. With special care，the examination can be completed smoothly.