关键词: 肌间沟臂丛神经阻滞, 甲哌卡因, 罗哌卡因, 锁骨骨折

Abstract: ［Abstract］ Objective To compare the efficacy of 1% Mepivacaine with 0.5% ropivacaine on brachial plexus nerve block in clavicle fracture surgery. Methods Thirty adult patients（ASAI~II）undergoing clavicle fracture surgery were randomly divided into two groups（n=15），1% mepivacaine group（group M）and 0.5% ropivacaine group（group R）. Patients in two groups both acceptted brachial plexus nerve block guided by nerve stimulator，and patients in group M and group R were injected 1% mepivacaine or 0.5% ropivacaine 25 ml separately. The hemodynamic，sensory and motor block onset and recovery time， postoperative VAS score，adverse reactions and anesthesia satisfaction were observed in the two groups. Results Compared with group R，the onset time of sensory and motor block was shortened in group M， the time of block recovery was shortened（P<0.05），and the scores of 6 h and 12 h were increased（P< 0.05）after operation（VAS < 0）. Conclusion Brachial plexus nerve block with 1% mepivacaine and 0.5% ropivacaine both can satisfy clavicle fracture surgery. The use of 1% mepivacaine was faster than the 0.5% ropivacaine，and the sensory and motor recovery was earlier in group M，which was beneficial to the early stage of operation，but the analgesic effect was less than 0.5% ropivacaine.

Key words: brachial plexus nerve block, clavicle fracture, ropivacaine, mepivacaine