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岭南现代临床外科 ›› 2018, Vol. 18 ›› Issue (02): 123-127.DOI: 10.3969/j.issn.1009-976X.2018.02.001

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HER2阳性转移性乳腺癌治疗年度进展

柴洁,姚和瑞*   

  1. 中山大学孙逸仙纪念医院
  • 通讯作者: 姚和瑞
  • 基金资助:

    国家自然科学基金;国家自然科学基金;国家自然科学基金;广东省自然科学基金;广州市科技计划;广州市科技计划

Annual progress of HER2 positive metastatic breast cancer

CHAI Jie, YAO Herui   

  1. Breast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China
  • Online:2018-04-20 Published:2018-04-20
  • Contact: YAO Herui

摘要: 乳腺癌是我国女性发病率最高的恶性肿瘤,其中HER2阳性转移性乳腺癌在晚期乳腺癌占比为25%~30%。HER2阳性乳腺癌患者预后差,如何提高HER2阳性转移性乳腺癌的治疗效果,包括优化靶向治疗、化疗药物的选择、后线治疗的策略等具有重要的临床意义。本文基于2017年各大乳腺癌会议,针对HER2阳性转移性乳腺癌在临床中的常见问题,阐述HER2阳性转移性乳腺癌治疗策略的新进展。

关键词: HER2阳性, 转移性乳腺癌, 靶向优化, 年度进展

Abstract: Breast cancer is one of the most common malignant disease in China. HER2 positive meta?static breast cancer accounted for 25% to 30%. The prognosis of HER2 positive metastatic breast cancer is poor, how to improve the therapeutic effect of HER2 positive metastatic breast cancer have vital clinical-significance, including optimize targeted therapy, selection of chemotherapy and strategy beyond first-line therapy. This article based on the 2017 breast cancer conference and reviewed the latest progress of HER2 positive metastatic breast cancer.

Key words: annual progress, HER2 positive, metastatic breast cancer, targeted optimization

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