关键词: 胰十二指肠切除术 , 腹腔镜手术

Abstract: Objective To evaluate the curative effects of laparoscopic pancreaticoduodenectomy（LPD），and discuss the safety and feasibility of LPD. Methods Retrospective analysis was conducted in clinical data of pancreaticoduodenectomy from January 2012 to December 2016，including 22 cases of laparoscopic pancreaticoduodenectomy and 21 cases of open pancreaticoduodenectomy（OPD）. The related outcomes of the two groups were compared ，which included operation time ，intraoperative blood loss ， intraoperative blood transfusion rate，postoperative anal exhaust time，postoperative hospital stay and postoperative complication. Results The laparoscopic group had significantly longer operation time（414.0±31.0 min vs. 263.8±34.4 min，t=11.634，P<0.001），however，shorter intraoperative blood loss（176.0±50.4 mL vs. 290.8±41.9 mL，t= -6.613，P=0.01），postoperative anal exhaust time（4.9±0.7 d vs. 6.7±0.8 d，t=-5.724，P=0.025）and postoperative hospital stay（17.3±2.0 d vs. 21.3±3.2 d，t=-3.514，P=0.002）than those in the open group（all P values were less than 0.05）. Conclusion Compared with OPD，LPD follows the principle of tumor occurring，which is safe and feasible.

Key words: laparoscopy, laparotomy, pancreaticoduodenectomy