关键词: PICC, 血栓, 导管相关性血流感染, 肿瘤患者

Abstract:

Objective To analyze the cause and pathogenic process in patients with both catheter? related bloodstream infection and catheter?related large vein thrombosis （CRLVT）. Methods The central line?associated bloodstream infection （CLABSI） were investigated from tumor patients with PICC between May 2015 to April 2016. Of 863 case with PICC catheter，two cases were diagnosed as CLABSI combined with thrombosis. Results Management of anticoagulation，thrombolysis，systemic anti infection and symptomatic supportive treatment were performed ，and the infection and bone marrow suppression were controlled ，and the local symptoms subsided. After discharge ，oral anticoagulation therapy was continued for one month，and no special discomfort was observed in follow?up. In the two CLABSI patients，poor compliance，poor health situation，local rash，decreased immunity might be the mainly pathogenic factors. Conclusion CLABSI patients should be paid attention to occurrence of thrombosis. Clinical nursing work should be targeted to avoid the possible risk factors in patients with PICC catheter.

Key words: cancer patients, thrombosis, PICC catheter?related bloodstream infections