关键词: 结核, 信号传导, 胸膜纤维化, 转化生长因子-β

Abstract: 【Abstract】 Pleural fibrosis is an important pathological change in tuberculous pleurisy progression. At present, most researches focus on the treatment of anti-tuberculosis drugs and pleural fiber-board stripped surgery, howerer the study of the mechanism of tuberculous pleural fibrosis is relatively little. In fact, pleural fibrosis has a more guiding significance for the prognosis of the disease. Studies have found that transforming growth factor beta(TGF-β) had been closely related with the tuberculous pleural fibrosis. This article reviews the role of TGF-β in the tuberculous pleural fibrosis, so as to further improve the theoretical understanding of tuberculous pleural fibrosis.

Key words: Pleural fibrosis, Signal transduction, Transforming growth factor beta, Tuberculous