关键词: 肾结石, 鹿角形结石, 经皮肾镜取石术, 治疗

Abstract: 【Abstract】〓Objective〓To investigate the effectivity and strategy of preoperative antibiotic use in treatment of staghorn calculi by percutaneous nephrolithotomy (PCNL). Methods〓Ninety-six patents who suffered from kidney staghorn calculi with no urinary tract infection were selected PCNL procedure. The patients were divided into two groups, Group A(n=49), preventive antibiotics administrated 1 hour before the operation, Group B (n=47), received cephalosporin treatment for 3 days before the operation. The incidence of bacteriuria and fever after the operation were compared. Results〓The surgical procedure of PCNL was completed in allpatients. The incidence of bacteriuria was 18.4%, fever 26.5% in group A, while the incidence of bacteriuria was 4.3%, postoperative fever 10.6% in group B. The incidence of bacteriuria and fever after the operation were lower in patients treated with cephalosporin 3 days before the operation than the patients with preventive treatment (P<0.05). Conclusion〓The management of preoperative antibiotics treatment for 3 days in the patient with kidney staghorn calculi but no clinical and laboratory infection evidence efficiently reduced the incidence of postoperative bacteriuria and fever after PCNL.

Key words: Treatment, Kidney stone, Percutaneous nephrolithotomy, Staghorn calculi