关键词: 骨质疏松, 椎体压缩骨折, 经皮椎体强化术

Abstract: 【Abstract】 Objective To evaluate the therapeutic efficacy,safety and surgical technique and tips of one-stage percutaneous vertebral augmentation of three or more vertebral body for multiple-level osteoporosis vertebral compression fracture. Methods A retrospective study was conducted to review twenty-six osteoporotic vertebral compression fracture patients who received one-stage percutaneous vertebral augmentation of three or more vertebral body. The outcome was considered by preoperatively and postoperatively by the Visual Analogue Scale (VAS) for pain relief. Clinical and image information of pre- and post-operation also be analyzed. Results All surgical procedures were performed successfully. The number of operating vertebrae in one time was 3,4,5 in 17,8,1 patients, respectively. The VAS changed from a mean preoperative score of 8.48±1.36 to a mean score of 3.08±1.24 on postoperative two days,1.96±1.17 three months after operation and 1.65±1.25 at final follow-up. Slight cement leakage was found in seven patients and one case was found the cement was leaked into perivertebral venous plexus, but without any clinical symptoms. Conclusion One-stage percutaneous vertebral augmentation of three or more vertebral body is safe and effective. It can be used in patients who are able to tolerate the surgery followed by professional assessment.

Key words: Osteoporosis, Vertebral compression fracture, Percutaneous vertebral augmentation