关键词: 经皮冠状动脉介入术, 冠心病, Meta分析, 心肌血运重建, 冠状动脉搭桥术

Abstract: 【Abstract】〓Objective〓By retrieving the articles published in Chinese, the Percutaneous Coronary Intervention (PCI) and Coronary Artery Bypass Grafting (CABG) were selected and compared between them, in whom all cases wene flowed up for more tham 24 months..The benefits and the risks of the cardiac revascularization via two different approaches were evaluated..The conclusion could be used as an evidence-based medicine base in the treatment of coronary heart disease..Methods〓The inclusion criteria, the exclusion criteria and the search strategy were made. The articles in the database of VIP Chinese Scientific & Technical Full Text Retrieval Database,.Wanfang Medical Database, CNKI and CBM were retrieved..The cohort study papers on the comparison of the cardiac revascularization via two different approaches were exacted. The quality of the papers was evaluated, and then the valid data was processed to the Meta analysis by RevMan 5.2 software..Results〓A total 33 papers were included in to the study literature with a total of 11,375 reported cases..In which,.the PCI group accounted for 6,125 cases,.while the CABG group accounted for 5,250 cases..The Meta-analysis reveals:.on the subject of the perioperative mortality,.the PCI group was significantly lower than the CABG group (1.22%, 4.12%), the OR value and the 95% CI was 0.29 (0.19-0.46), P<0.001. However the all-cause mortality during the whole follow-up period, there was no significant difference between the two groups (3.92%, 4.57%), the OR value and the 95% CI, 0.91 (0.7-1.10), P=0.33. On the revascularization rate, the PCI group was significantly higher than the CABG group (9.99%, 3.77%), the OR value and the 95% CI was 3.57 (2.62-4.87), P<0.001. On the incident of MACCE, the PCI group was significantly higher than the CABG group (17.94%, 12.35%), the OR value and the 95% CI is 1.62 (1.33-1.98), P<0.001. Conclusion〓The comparison of two methods of myocardial revascularization indicates that the PCI has the advantage in the aspects of the shorter perioperative period and the lower incidence of adverse events; however, the advantages of CABG is a better long-term prognosis and a lower incident of re-vascularization. During the decision making of the treatment of the coronary artery disease, the doctors should pay more attention to the disadvantages of each method, to choose the treatment plan with the long-term perspective.

Key words: CABG, Revascularization, Meta analysis, Coronary Artery Heart Disease, Percutaneous Coronary Intervention