关键词: 冷刀内切开, 钬激光, 后尿道狭窄

Abstract: 【Abstract】〓Objective〓To compare the clinical efficacy and safety between cold knife endoscopic incision and combined holmium laser with cold knife incision for posterior-urethral stricture. Methods Twenty-six cases of posterior-urethral stricture were assigned cold knife endoscopic incision only, while another 27 cases of posterior-urethral stricture patients were taken combined therapy with holmium laser incision and cold knife endoscopic incision. The average follow-up was 20 months (range 12-30 months). The post-operative clinical data and therapeutic results were compared and analyzed. Results〓All cases from both groups were treated successfully with no serious bleeding and severe complication. The maximal urinary flow rate in both group was improved after operation. The postoperative hospital stay and the mean operative time had no significant difference in two group (P>0.05). The recurrent stricture rate and reoperation rate of combined therapy group were lower than that of cold knife group (P<0.05). Conclusion〓Combined therapy of holmium laser endoscopic incision and cold knife incision for posterior-urethral stricture could be a safer and more effective minimally invasive therapeutic modality for posterior-urethral stricture, as compared with the simple cold knife endoscopic incision.

Key words: Cold knife endoscopic incision, Holmium lasers, Posterior-urethral stricture