关键词: 新辅助化疗, CRP, 乳腺癌

Abstract: 【Abstract】〓Objective〓To analyze the relationship between C reactive protein (CRP) and clinical pathobiiology factors before and after neoadjuvant chemotherapy. Methods〓This research retrospectively analyzed 215 patients, who were diagnosed as breast cancer in stage Ⅱ-Ⅲ, admitted in the Breast Cancer Department of our hospital and accepted NAC in January 2001 to June 2010. The relationship of CRP with clinicopathological characteristics as well as efficacy of prediction of pathologic complete response according to two different standards were statistically analyzed. Results Patients with pCR were in lower CRP value comparing with non-pCR patients. CRP reached a high efficacy in predicting pCR (the absence of all invasive disease in the breast tumor). Conclusion〓The protein level of CRP shows predictive value of pCR with neoadjuvantchemotherapy patients.

Key words: Neoadjuvant chemotherapy, CRP, Breast cancer