关键词: Narcotrend, 认知功能障碍, 术后并发症

Abstract: 【Abstract】〓Objective〓To investigate the role of Narcotrend (NT) monitor on postoperative cognitive impairment in elderly patients with laparoscopic chloecystectomy (LC). Methods〓Sixty cases of elderly patients under general anesthesia for laparoscopic chloecystectomy were randomized into two groups, the control group (n=30) and the NT group (n=30) according to the patients with or without NT monitor. The dosage of remifentanil and sevoflurane during anesthesia, operative time, extubation time, recovery time and incidence of postoperative dysfunction were recorded and analyzed. Results〓The dosage of remifentanil and sevoflurane in NT group were significantly lower than that of the control group, the difference was statistically significant (P<0.05). The incidence of Postoperative cognitive dysfunction in 24 h after surgery in NT patients was significantly lower than that of the control group (P<0.05), but not in the seventh day after surgery (P>0.05). Conclusion〓Narcotrend monitor during general anesthesia is instrumental to accurately judge the depth of sedation and effectively reduce the incidence of postoperative dysfunction in elderly patients undergoing LC.

Key words: Narcotrend monitoring, Cognitive dysfunction, Postoperative complications